4 Things to Know Before Trying GLP-1s for Weight Loss

GLP1- weight loss medications are everywhere right now. Social media, TV ads, maybe even your own conversations with friends.

They promise quick results — but are they really the right choice for you?

“These medications can be life-changing for the right patient,” says Devika Umashanker, MD, medical director of medical weight loss at Hartford HealthCare. “But they should always be used under the guidance of a physician. It’s not safe to buy them online or use them casually if you don’t meet the medical criteria.”

Here’s what Dr. Umashanker wants you to know before you decide.

1. They’re designed for people with obesity or related health conditions.

Weight loss medications aren’t for everyone.

They’re typically prescribed if your body mass index (BMI) is 30 or higher, or 27 with weight related conditions like diabetes, high blood pressure or sleep apnea.

“If you do not meet the criteria, these medications are not recommended,” Dr. Umashanker cautions. “They come with risks and side effects that outweigh the benefits for people who don’t need them.”

> Related: Which Weight Loss Drug Is Right for Me? 

2. Medication is just one piece of the puzzle.

Think of weight loss medication as one tool in a much bigger toolbox.

“Lifestyle changes are still the cornerstone of weight management,” says Dr. Umashanker. “Medication can help reduce appetite or cravings, but long-term success comes from building sustainable habits.”

That means healthy eating, regular movement and behavior shifts — with medication as support and a tool, not a shortcut.

3. They can come with side effects.

Like any medication, weight loss medications aren’t risk-free. They can cause nausea, digestive issues, headaches, vision impairment or even newly formed thyroid nodules which require surveillance.

That’s where your provider comes in.

“Your doctor will monitor your health, adjust doses if needed, and make sure the medication is safe to continue,” says Dr. Umashanker. “That oversight is critical — especially if you’re taking other medications.”

> Related: 6 Other Conditions That Weight Loss Drugs Help With

4. Skip the sketchy online shortcuts.

The rise in popularity has led to a rise in counterfeits — pills sold online that may be unregulated, contaminated or outright fake.

“Always obtain a prescription for weight loss medications from a licensed provider who knows your medical history,” stresses Dr. Umashanker. “Anything else is unsafe.”

> Related: Why Most Diets Fail — And What to Do Instead

Want to lose weight, but don’t qualify for medication?

It’s common to struggle with weight.

“If you don’t meet the medical criteria, weight loss medications are never the right path,” says Dr. Umashanker. “But there are still plenty of safe, effective strategies you can use.”

Here are a few practical tips:

• Focus on small, steady changes. Swapping soda for water, adding an extra 10 minutes of walking each day, or getting more sleep can have a real impact over time.
• Pay attention to your mental health. “Weight struggles can feel overwhelming, even if you’re not considered overweight or obese,” Dr. Umashanker notes. “If you’re constantly feeling unhappy with your body, reaching out to a counselor or support group can be just as important as changes in nutrition.”
• Think long-term. Quick fixes rarely last. Aim for habits you can maintain, not drastic changes that feel unsustainable.

“Every patient’s journey is unique,” says Dr. Umashanker. “When used correctly, under medical supervision, these medications can help — but they should never replace a healthy lifestyle or be taken without proper guidance.”

And remember — weight is only one piece of health. Building strength, boosting mood, and reducing stress are all just as important.

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